Tirzepatide (GLP-1T) 10mg

Tirzepatide (GLP-1T) 10mg — synthetic dual-agonist research peptide

Tirzepatide is a synthetic dual-receptor agonist peptide studied for its binding activity at two metabolic receptors: glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1). This dual-incretin profile positions it between mono-agonists like semaglutide and triple-agonists like retatrutide, and makes it a common reference compound in comparative receptor-pharmacology research.

For laboratory research use only. Not for human or animal consumption. Tirzepatide is offered as a research reference material and is not approved by SBR Labs or by regulators for any human or veterinary use.

Product specifications

• Class: synthetic dual GIP / GLP-1 receptor agonist peptide
• Amount per vial: 10mg lyophilized powder
• Purity target: ≥98% by HPLC (third-party verified per lot)
• Physical form: lyophilized white to off-white powder, sealed against light and moisture
• Reconstitution: commonly reconstituted with bacteriostatic water for laboratory work

Why dual GIP/GLP-1 agonism matters in research

Tirzepatide's simultaneous activity at both incretin receptors is what distinguishes it from single-receptor comparators like semaglutide:

• GLP-1 receptor — pancreatic beta-cell insulin secretion pathways, gastric emptying, and cAMP/PKA downstream signaling
• GIP receptor — additional incretin signaling not covered by GLP-1 mono-agonists, plus adipocyte lipid handling research
• Combined activity — reference research on dual-agonist pharmacokinetics, receptor-affinity ratios, and downstream signaling amplitude

Preclinical research areas

• Dual GIP/GLP-1 receptor agonism in receptor-binding assays
• Incretin hormone signaling pathways in animal models
• Pancreatic beta-cell insulin secretion pathways in vitro
• Gastric emptying rate and GI motility mechanisms in animal models
• Downstream receptor signaling (cAMP/PKA pathway) in cell culture
• Pharmacokinetic and receptor-affinity characterization vs. GLP-1 mono-agonists

Purity, testing, and COA

Every lot of tirzepatide shipped by SBR Labs is characterized by an independent third-party laboratory. Each COA reports peptide identity by mass spectrometry, purity by reverse-phase HPLC, and appearance. Current and prior lot COAs are available at /pages/coas. For a walkthrough on interpreting a peptide COA, see the SBR Labs guide.

Handling and reconstitution

• Store the sealed lyophilized vial at −20 °C, protected from light and moisture
• Reconstitute with bacteriostatic water or sterile water per your laboratory SOP
• After reconstitution, refrigerate at 2–8 °C and aliquot to single-use volumes
• Record lot number, reconstitution date, and solvent for reproducibility
• See the full SBR Labs handling & storage reference

Related research materials

• Semaglutide (GLP-1S) 10mg — GLP-1 mono-agonist for comparative research
• Retatrutide (GLP-3R) 10mg — triple agonist with added glucagon receptor activity
• Bacteriostatic Water 10ml — sterile diluent for reconstitution

For Laboratory Research Use Only. Not for human or veterinary use. Not a drug, dietary supplement, or cosmetic. Not intended to diagnose, treat, cure, or prevent any disease. Not for in-vivo use of any kind outside of a controlled research setting. Keep out of reach of children. By purchasing, you certify that you are a qualified researcher or research institution acquiring this product solely for in vitro laboratory research, and that you accept sole responsibility for compliance with all applicable local, state, and federal laws and regulations.