{"product_id":"retatrutide","title":"Retatrutide (GLP-3R)","description":"\u003ch2\u003eRetatrutide (GLP-3R) — synthetic triple-agonist research peptide\u003c\/h2\u003e\n\n\u003cp\u003eRetatrutide is a synthetic \u003cstrong\u003etriple-receptor agonist\u003c\/strong\u003e peptide studied for its activity at three metabolic receptors simultaneously: \u003cstrong\u003eglucagon-like peptide-1 (GLP-1)\u003c\/strong\u003e, \u003cstrong\u003eglucose-dependent insulinotropic polypeptide (GIP)\u003c\/strong\u003e, and the \u003cstrong\u003eglucagon receptor\u003c\/strong\u003e. This tri-agonist profile distinguishes it from dual agonists like tirzepatide (GIP\/GLP-1) and mono-agonists like semaglutide (GLP-1 only), and makes it a subject of active research in receptor pharmacology, energy expenditure, and hepatic lipid metabolism.\u003c\/p\u003e\n\n\u003ch3\u003eCertificate of analysis — current lot on file\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eRetatrutide 10mg\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eProduct:\u003c\/strong\u003e Retatrutide 10mg\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLaboratory:\u003c\/strong\u003e Freedom Diagnostics (independent third party)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAccession number:\u003c\/strong\u003e 2607150703\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReported lot:\u003c\/strong\u003e RT10\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReported purity:\u003c\/strong\u003e 99.52%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReported content:\u003c\/strong\u003e 12.82mg\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReport date:\u003c\/strong\u003e July 18, 2026\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eRetatrutide 20mg\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eProduct:\u003c\/strong\u003e Retatrutide 20mg\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLaboratory:\u003c\/strong\u003e Janoshik (independent third party)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTask number:\u003c\/strong\u003e 200517\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReported batch:\u003c\/strong\u003e RT20260602\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReported purity:\u003c\/strong\u003e 99.507%\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReported content:\u003c\/strong\u003e 22.24mg\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReport date:\u003c\/strong\u003e July 7, 2026\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eVerify these reports with the lab: \u003ca href=\"https:\/\/coas.freedomdiagnosticstesting.com\/LPPe2607150703.pdf\" target=\"_blank\" rel=\"noopener\"\u003eopen the original Freedom Diagnostics 10mg report\u003c\/a\u003e and \u003ca href=\"https:\/\/verify.janoshik.com\/tests\/200517_1AGCQBZHJFEB\" target=\"_blank\" rel=\"noopener\"\u003eopen the original Janoshik 20mg report\u003c\/a\u003e. Both are also listed on the SBR Labs Certificates of Analysis page (\u003ca href=\"\/pages\/coas#coa-retatrutide-10mg\"\u003e10mg\u003c\/a\u003e, \u003ca href=\"\/pages\/coas#coa-retatrutide-20mg\"\u003e20mg\u003c\/a\u003e). A report for the 15mg strength is not yet posted; please \u003ca href=\"\/pages\/contact\"\u003econtact us\u003c\/a\u003e before ordering if you need lot documentation for 15mg. To check the identity, lot, and purity fields yourself, see \u003ca href=\"\/blogs\/news\/how-to-read-a-peptide-certificate-of-analysis\"\u003ehow to read a peptide certificate of analysis\u003c\/a\u003e and \u003ca href=\"\/blogs\/news\/how-to-verify-peptide-purity-reports\"\u003ehow to verify peptide purity reports\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor laboratory research use only.\u003c\/strong\u003e Not for human or animal consumption. Retatrutide is an investigational research compound and is not approved by the FDA or any comparable regulator for any use.\u003c\/p\u003e\n\n\u003ch3\u003eProduct specifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eClass:\u003c\/strong\u003e synthetic triple-receptor agonist peptide (GLP-1 \/ GIP \/ glucagon)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAmount per vial:\u003c\/strong\u003e 10mg, 15mg, or 20mg lyophilized powder (select strength above)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity target:\u003c\/strong\u003e ≥98% by HPLC (third-party reports on file for 10mg and 20mg)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePhysical form:\u003c\/strong\u003e lyophilized white to off-white powder, sealed against light and moisture\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReconstitution:\u003c\/strong\u003e commonly reconstituted with \u003ca href=\"https:\/\/sbresearchlabs.com\/products\/bac-water\"\u003ebacteriostatic water\u003c\/a\u003e for laboratory work\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eWhy the triple-agonist profile matters\u003c\/h3\u003e\n\n\u003cp\u003eRetatrutide's simultaneous activity at three receptors gives it a distinct research signature versus mono- and dual-agonist peptides:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGLP-1 receptor\u003c\/strong\u003e — pancreatic beta-cell signaling, incretin-pathway effects, gastric emptying\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGIP receptor\u003c\/strong\u003e — additional incretin signaling and adipocyte energy handling\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGlucagon receptor\u003c\/strong\u003e — hepatic lipid metabolism, thermogenesis, and energy expenditure — a pathway absent from semaglutide and tirzepatide research\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eThe glucagon-receptor component is what makes retatrutide of particular interest for research into hepatic lipid handling and energy-expenditure pathways.\u003c\/p\u003e\n\n\u003ch3\u003ePreclinical research areas\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eTriple GLP-1 \/ GIP \/ glucagon receptor agonism in receptor-binding assays\u003c\/li\u003e\n\u003cli\u003eEnergy expenditure and thermogenesis pathways in animal models\u003c\/li\u003e\n\u003cli\u003eHepatic lipid metabolism and glucagon-receptor signaling research\u003c\/li\u003e\n\u003cli\u003eIncretin-pathway and pancreatic beta-cell signaling in vitro\u003c\/li\u003e\n\u003cli\u003eGastric emptying and GI motility mechanism studies\u003c\/li\u003e\n\u003cli\u003ePharmacokinetic and receptor-affinity characterization\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003ePurity, testing, and COA\u003c\/h3\u003e\n\n\u003cp\u003eIndependent third-party reports are on file for the 10mg strength (Freedom Diagnostics, lot RT10) and the 20mg strength (Janoshik, batch RT20260602). The 15mg report is not yet posted. Posted reports are available on the \u003ca href=\"\/pages\/coas\"\u003eCertificates of Analysis page\u003c\/a\u003e. To learn how to interpret a peptide COA, see the \u003ca href=\"https:\/\/sbresearchlabs.com\/blogs\/news\/how-to-read-a-peptide-certificate-of-analysis\"\u003eSBR Labs guide to reading a peptide COA\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch3\u003eHandling and reconstitution\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eStore the sealed lyophilized vial at −20 °C, protected from light and moisture\u003c\/li\u003e\n\u003cli\u003eReconstitute with bacteriostatic water or sterile water per your laboratory SOP\u003c\/li\u003e\n\u003cli\u003eAfter reconstitution, refrigerate at 2–8 °C and aliquot to single-use volumes\u003c\/li\u003e\n\u003cli\u003eRecord lot number, reconstitution date, and solvent for reproducibility\u003c\/li\u003e\n\u003cli\u003eSee the full \u003ca href=\"\/blogs\/news\/research-peptide-handling-storage-laboratory-reference\"\u003eSBR Labs handling \u0026amp; storage reference\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eRelated research materials\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/sbresearchlabs.com\/products\/tirzepatide\"\u003eTirzepatide (GLP-1T) 10mg\u003c\/a\u003e — dual GIP\/GLP-1 agonist for comparative research\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/sbresearchlabs.com\/products\/semaglutide\"\u003eSemaglutide (GLP-1S) 10mg\u003c\/a\u003e — GLP-1 mono-agonist reference\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/sbresearchlabs.com\/products\/bac-water\"\u003eBacteriostatic Water 10ml\u003c\/a\u003e — sterile diluent for reconstitution\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp style=\"text-align: center;\"\u003eFor Laboratory Research Use Only. Not for human or veterinary use. Not a drug, dietary supplement, or cosmetic. Not intended to diagnose, treat, cure, or prevent any disease. Not for in-vivo use of any kind outside of a controlled research setting. Keep out of reach of children. By purchasing, you certify that you are a qualified researcher or research institution acquiring this product solely for in vitro laboratory research, and that you accept sole responsibility for compliance with all applicable local, state, and federal laws and regulations.\u003c\/p\u003e","brand":"SBR Labs","offers":[{"title":"10mg","offer_id":53224515273071,"sku":"SBR-RETA-10MG","price":64.99,"currency_code":"USD","in_stock":true},{"title":"15mg","offer_id":53218181349743,"sku":"SBR-RETA-15MG","price":79.99,"currency_code":"USD","in_stock":true},{"title":"20mg","offer_id":53511586382191,"sku":"SBR-RETA-20MG","price":119.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0976\/2491\/6335\/files\/IMG-4598.png?v=1785445086","url":"https:\/\/sbresearchlabs.com\/products\/retatrutide","provider":"SBR Labs","version":"1.0","type":"link"}