{"product_id":"glp-1s","title":"Semaglutide (GLP-1S) 10mg","description":"\u003ch2\u003eSemaglutide (GLP-1S) 10mg — synthetic GLP-1 receptor agonist\u003c\/h2\u003e\n\n\u003cp\u003eSemaglutide is a synthetic \u003cstrong\u003eglucagon-like peptide-1 (GLP-1) receptor agonist\u003c\/strong\u003e studied for its binding activity at the GLP-1 receptor. As a single-receptor agonist, it serves as the standard reference compound in comparative research against dual agonists (tirzepatide, GIP\/GLP-1) and triple agonists (retatrutide, GIP\/GLP-1\/glucagon).\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eFor laboratory research use only.\u003c\/strong\u003e Not for human or animal consumption. Semaglutide is offered here as a research reference material.\u003c\/p\u003e\n\n\u003ch3\u003eProduct specifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eClass:\u003c\/strong\u003e synthetic GLP-1 receptor mono-agonist peptide\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAmount per vial:\u003c\/strong\u003e 10mg lyophilized powder\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePurity target:\u003c\/strong\u003e ≥98% by HPLC (third-party verified per lot)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePhysical form:\u003c\/strong\u003e lyophilized white to off-white powder, sealed against light and moisture\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eReconstitution:\u003c\/strong\u003e commonly reconstituted with \u003ca href=\"https:\/\/sbresearchlabs.com\/products\/bac-water\"\u003ebacteriostatic water\u003c\/a\u003e for laboratory work\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eWhy semaglutide is the reference GLP-1 agonist in research\u003c\/h3\u003e\n\n\u003cp\u003eSemaglutide is the most-characterized GLP-1 mono-agonist in the modern research literature, which makes it the natural comparator for newer multi-agonist peptides:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eReceptor specificity\u003c\/strong\u003e — activity confined to the GLP-1 receptor, allowing clean isolation of GLP-1 pathway effects\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDownstream signaling\u003c\/strong\u003e — well-characterized cAMP\/PKA activation pathway in beta-cell and enteric research models\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eComparator role\u003c\/strong\u003e — reference standard for evaluating incremental effects of GIP and glucagon receptor activity in dual- and triple-agonist research\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003ePreclinical research areas\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eGLP-1 receptor agonism in receptor-binding assays\u003c\/li\u003e\n\u003cli\u003eIncretin hormone signaling pathways in animal models\u003c\/li\u003e\n\u003cli\u003ePancreatic beta-cell insulin secretion pathways in vitro\u003c\/li\u003e\n\u003cli\u003eGastric emptying rate and GI motility mechanisms in animal models\u003c\/li\u003e\n\u003cli\u003eDownstream receptor signaling (cAMP\/PKA pathway) in cell culture\u003c\/li\u003e\n\u003cli\u003ePharmacokinetic and receptor-affinity characterization as a mono-agonist reference\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003ePurity, testing, and COA\u003c\/h3\u003e\n\n\u003cp\u003eEvery lot of semaglutide is characterized by an independent third-party laboratory. Each COA reports peptide identity by mass spectrometry, purity by reverse-phase HPLC, and appearance. Current and prior lot COAs are available at \u003ca href=\"https:\/\/sbresearchlabs.com\/pages\/coas\"\u003e\/pages\/coas\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch3\u003eHandling and reconstitution\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eStore the sealed lyophilized vial at −20 °C, protected from light and moisture\u003c\/li\u003e\n\u003cli\u003eReconstitute with bacteriostatic water or sterile water per your laboratory SOP\u003c\/li\u003e\n\u003cli\u003eAfter reconstitution, refrigerate at 2–8 °C and aliquot to single-use volumes\u003c\/li\u003e\n\u003cli\u003eRecord lot number, reconstitution date, and solvent for reproducibility\u003c\/li\u003e\n\u003cli\u003eSee the full \u003ca href=\"https:\/\/sbresearchlabs.com\/pages\/research-handling-storage-guide\"\u003eSBR Labs handling \u0026amp; storage reference\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eRelated research materials\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/sbresearchlabs.com\/products\/glp-1t\"\u003eTirzepatide (GLP-1T) 10mg\u003c\/a\u003e — dual GIP\/GLP-1 agonist for comparative research\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/sbresearchlabs.com\/products\/glp-3r\"\u003eRetatrutide (GLP-3R) 10mg\u003c\/a\u003e — triple GLP-1 \/ GIP \/ glucagon agonist\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/sbresearchlabs.com\/products\/bac-water\"\u003eBacteriostatic Water 10ml\u003c\/a\u003e — sterile diluent for reconstitution\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp style=\"text-align: center;\"\u003eFor Laboratory Research Use Only. Not for human or veterinary use. Not a drug, dietary supplement, or cosmetic. Not intended to diagnose, treat, cure, or prevent any disease. Not for in-vivo use of any kind outside of a controlled research setting. Keep out of reach of children. By purchasing, you certify that you are a qualified researcher or research institution acquiring this product solely for in vitro laboratory research, and that you accept sole responsibility for compliance with all applicable local, state, and federal laws and regulations.\u003c\/p\u003e","brand":"SBR Labs","offers":[{"title":"10mg","offer_id":53479541342575,"sku":"SBR-SEMA-10MG","price":38.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0976\/2491\/6335\/files\/IMG-5319.png?v=1789496532","url":"https:\/\/sbresearchlabs.com\/products\/glp-1s","provider":"SBR Labs","version":"1.0","type":"link"}